Dr. Daniel J. Siegwart, Principal Investigator
Daniel J. Siegwart is the W. Ray Wallace Distinguished Chair in Molecular Oncology Research and Professor at the University of Texas Southwestern Medical Center. His research program is focused on developing advanced lipid and polymer based systems with precise control over structure and responsiveness for applications in drug delivery, imaging, genetic diseases, and cancer.
2023 – Present: Professor, University of Texas Southwestern Medical Center, Department of Biomedical Engineering, Department of Biochemistry, Simmons Comprehensive Cancer Center
2024: Co-founder, Pegasus Bio
2023: Co-founder, Signify Bio
2023: Co-founder, Jumble Therapeutics
2022 – Present: Director, Program in Genetic Drug Engineering
2022 – Present: Director, Drug Delivery Program in Biomedical Engineering, Department of Biomedical Engineering
2020 – Present: Co-Director, Chemistry and Cancer Program, SCCC
2018 – 2023: Associate Professor, University of Texas Southwestern Medical Center, Department of Biochemistry, Simmons Comprehensive Cancer Center
2015: Co-founder, ReCode Therapeutics
2012 – 2018: Assistant Professor, University of Texas Southwestern Medical Center, Department of Biochemistry, Simmons Comprehensive Cancer Center
2008 – 2012: Postdoctoral Fellow, Massachusetts Institute of Technology (MIT), Department of Chemical Engineering, Koch Institute for Integrative Cancer Research (Advisors: Institute Professor Robert Langer and Professor Daniel Anderson)
2006: EAPSI Fellow Materials Engineering, University of Tokyo, (Advisor: Professor Kazunori Kataoka)
2003 – 2008: M.S., Ph.D. Chemistry, Carnegie Mellon University (CMU), (Advisor: University Professor Krzysztof Matyjaszewski)
1999 – 2003: B.S. Biochemistry, Lehigh University
Awards and Fellowships:
| Year(s) | Name of Honor/Award | Awarding Organization |
| 2003 | Chemistry Department Research Honors | Lehigh University |
| 2005 – 2008 | The Joseph A. Solomon Memorial Fellowship in Chemistry | Carnegie Mellon University |
| 2006 | East Asia and Pacific Summer Institutes (EAPSI) Fellowship | National Science Foundation (NSF) |
| 2010 – 2012 | Ruth L. Kirschstein National Research Service Award (NRSA) F32 Postdoctoral Fellowship | National Institutes of Health (NIH) |
| 2012 – 2016 | CPRIT Scholar Award | Cancer Prevention and Research Institute of Texas (CPRIT) |
| 2014 | Award in Cancer Research | Friends of the Comprehensive Cancer Center |
| 2017 | Research Scholar Award | American Cancer Society (ACS) |
| 2018 | Young Innovator Award in Nanobiotechnology | Editorial Board of Nano Research |
| 2019 | Biomaterials Science Emerging Investigator | Editorial Board of Biomaterials Science |
| 2021 | Special Recognition Award | Chinese Institute of Engineers (USA) Dallas-Fort Worth Chapter |
| 2021 | Gilliam Fellow for Advanced Study (adviser-student pair) | Howard Hughes Medical Institute (HHMI) |
| 2022 | W. Ray Wallace Distinguished Chair in Molecular Oncology Research | UT Southwestern Medical Center |
| 2022 | Elected to the American Institute for Medical and Biological Engineering (AIMBE) College of Fellows | The American Institute for Medical and Biological Engineering (AIMBE) |
| 2023 | Elected to the Controlled Release Society (CRS) College of Fellows | Controlled Release Society (CRS) |
| 2024, 2025 | Highly Cited Researcher Award | Clarivate |
| 2024 | Victor J. Dzau Emerging Leaders in Health and Medicine (ELHM) Scholar | National Academy of Medicine (NAM) |
| 2024 | Elected to the National Academy of Inventors (NAI) (Fellow) | National Academy of Inventors (NAI) |
| 2026 | Dr. Fritz Eckstein Mid-Career Achievement Award | Oligonucleotide Therapeutics Society (OTS) |