Dr. Daniel J. Siegwart, Principal Investigator

Daniel J. Siegwart is the W. Ray Wallace Distinguished Chair in Molecular Oncology Research and Professor at the University of Texas Southwestern Medical Center. His research program is focused on developing advanced lipid and polymer based systems with precise control over structure and responsiveness for applications in drug delivery, imaging, genetic diseases, and cancer.

2023 – Present: Professor, University of Texas Southwestern Medical Center, Department of Biomedical Engineering, Department of Biochemistry, Simmons Comprehensive Cancer Center

2023: Co-founder, Signify Bio

2023: Co-founder, Jumble Therapeutics

2022 – Present: Director, Program in Genetic Drug Engineering

2022 – Present: Director, Drug Delivery Program in Biomedical Engineering, Department of Biomedical Engineering

2020 – Present: Co-Director, Chemistry and Cancer Program, SCCC

2018 – 2023: Associate Professor, University of Texas Southwestern Medical Center, Department of Biochemistry, Simmons Comprehensive Cancer Center

2015: Co-founder, ReCode Therapeutics

2012 – 2018: Assistant Professor, University of Texas Southwestern Medical Center, Department of Biochemistry, Simmons Comprehensive Cancer Center

2008 – 2012: Postdoctoral Fellow, Massachusetts Institute of Technology (MIT), Department of Chemical Engineering, Koch Institute for Integrative Cancer Research (Advisors: Institute Professor Robert Langer and Professor Daniel Anderson)

2003 – 2008: Ph.D. Chemistry, Carnegie Mellon University (CMU), (Advisor: University Professor Krzysztof Matyjaszewski)

1999 – 2003: B.S. Biochemistry, Lehigh University

Awards and Fellowships: National Academy of Inventors (NAI) Fellow (2024), National Academy of Medicine (NAM) Emerging Leaders in Health and Medicine (ELHM) Scholar (2024), Controlled Release Society (CRS) College of Fellows (2023), American Institute for Medical and Biological Engineering (AIMBE) College of Fellows (2022), Howard Hughes Medical Institute (HHMI) Gilliam Fellowship for Advanced Study (adviser-student pair) (2021), Biomaterials Science Emerging Investigator (2019), Young Innovator Award in Nanobiotechnology (2018), American Cancer Society (ACS) Research Scholar (2017), Friends of the Comprehensive Cancer Center Award in Cancer Research (2014), Cancer Prevention and Research Institute of Texas (CPRIT) Scholar Award (2012), National Institutes of Health (NIH) Ruth L. Kirschstein National Research Service Award (NRSA) F32 Postdoctoral Fellowship (2010), National Science Foundation (NSF) East Asia and Pacific Summer Institutes (EAPSI) Fellowship at The University of Tokyo (Advisor: Professor Kazunori Kataoka) (2006), The Joseph A. Solomon Memorial Fellowship in Chemistry (CMU) (2005), Chemistry Department Research Honors (Lehigh) (2003)